Amoxycillin (Amoxil)

Type of Medication: Antibiotic

Indications: Treatment of respiratory tract exacerbations due to sensitive H.influenzae and Streptococcal infections

Side Effects:  Nausea, vomiting, diarrhoea,rarley antibiotic associated colitis, hypersensitivity reaction

Route of administration: Adult (Intravenous)

Dose:500mg to 1g 3 – 4 times a day

Administration: Bolus: dissolve 500 mg in 10 ml WFI or 1g in 20 ml WFI and administer over 3-4 minutes. Can be administered as infusion in 100 ml glucose 5 % or saline 0.9% over 30-60 minutes

Route of administration: Adult (Oral)

Dose:500-1000mg tds

Administration: Available as 250 or 500 mg capsules or as 125 mg/1.25 ml, 125 mg/5 ml, 250 mg/5ml syrup or suspension

Route of administration: Paediatric (Intravenous)

Dose:50 mg/kg/day in 3 divided doses. May be doubled if necessary. Max 1 g tds


Route of administration: Paediatric (Oral)

Dose:0-1 yrs 62.5 mg tds 1-4 yrs 125 mg tds 5-12 yrs 250 mg tds


Examples of Drug Interactions

Interacting drug: Allopurinol

increased risk of rash with concomitant use.

Interacting drug: Methotrexate

increases methotrexate toxicity (reduced secretion)

Interacting drug: Probenecid

reduces penicillin excretion