Type of Medication: Antibiotic

Indications: Taurolidine is an unlicensed product available as an intraperitoneal lavage (Taurolin®). It acts as an antibiotic and an anti-endotoxin with a broad spectrum of activity against Gram negative and positive bacteria and fungi. Taurolidine is active in vitro against P. aeruginosa and Burkholderia Cepacia Complex (Bcc). It is presently used as nebulised therapy in transplant patients with B.cepacia

Side Effects:  Burning, hypersensitivity, bronchospasm

Route of administration: Adult (Nebulised)

Dose: Freeman hospital protocol – 2-3 ml of 2% solution twice daily

Administration: Must do a test dose as a significant number of patients get bronchospasm. 2 ml of 2% diluted with 2 ml sterile water with pre and post lung function

Examples of some Drug Interactions