Type of Medication: Bile acid
Indications: Improving bile flow in patients with liver impairment
Side Effects: Diarrhoea, nausea, vomiting, pruritis, gallstone calcification
Route of administration: Adult (Oral)
Dose:20mg/kg/day in 2-3 divided doses with or after food. Up to a maximum of 450mg tds.
Administration: In Leeds we prescribe a combination of ursodeoxycholic acid with taurine. Avaliable as 150mg tablets, 250mg capsules and 250 mg/5ml suspension
Route of administration: Paediatric (Oral)
Dose:20mg/kg/day in 2-3 divided doses, with or after food. Up to a maximum of 450mg tds.
Examples of some Drug Interactions
Interacting drug: ciclosporin
Increases ciclosporin plasma concentrations – unpredictable and does not occur in all patients.